Genetics of Ankylosing Spondylitis. What’s the risk for your child?
Ankylosing spondylitis (AS) is a type of arthritis that affects the spine and pelvis. Changes in genes contribute to the risk of people developing ankylosing spondylitis.
One gene makes a strong contribution to the risk of arthritis, it’s called HLA-B27. Around 70-80% of people with ankylosing spondylitis have the HLA-B27 gene.
What does that mean for the children of people with ankylosing spondylitis?
Well luckily the risk is pretty low and there are some pretty good treatments for ankylosing spondylitis, so I don’t think that people should be making decisions to have children or not have children based on the fact they have ankylosing spondylitis.