11 Diseases That Mimic Rheumatoid Arthritis
Pseudogout – CPPD crystal deposition disease is linked to an array of clinical manifestations. It can be asymptomatic, gout-like (pseudogout), rheumatoid arthritis–like, or osteoarthritis-like. Pseudogout is distinguished by acute attacks of synovitis that mimic gout. Synovial fluid analysis is used for the differential diagnosis.
Sjogren’s Syndrome – Sjogren’s syndrome is an autoimmune, inflammatory disease. It can occur as a primary condition with no other rheumatic disease or as a secondary condition along with another rheumatic condition. Primary Sjogren’s syndrome can mimic rheumatoid arthritis. Approximately 60 to 70 percent of primary Sjogren’s patients are positive for rheumatoid factor. There also typically is pain, stiffness, and mild swelling of the joints. Specialized testing can help distinguish between Sjogren’s syndrome and rheumatoid arthritis.
Sarcoidosis – Sarcoidosis can manifest with synovitis in several joints and may be rheumatoid factor positive. But, other characteristics help distinguish it from rheumatoid arthritis. In some cases, a tissue biopsy may be required to establish the diagnosis.